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Article

The inhibition of lung cancer cell migration by AhR-regulated autophagy

14 Feb 2017

Abstract excerpt

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is highly expressed in multiple organs and tissues. Whereas AhR mediates the metabolism of xenobiotic and endogenous compounds, its novel function in cancer epithelial-mesenchymal transition (EMT) remains controversial. Autophagy also participates in tumour progression through its functions in cell homeostasis and facilitates...

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PMID: 28195146
DOI: 10.1038/srep41927

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