Article

Nanobiopolymer for Direct Targeting and Inhibition of EGFR Expression in Triple Negative Breast Cancer

2020-06-14

Abstract excerpt

<p>AbstractTreatment options for triple negative breast cancer (TNBC) are generally limited to cytotoxic chemotherapy. Recently, antiepidermalgrowth factor receptor (EGFR) therapy has been introduced for TNBC patients. We engineered a novelnanobioconjugate based on a poly(b-L-malic acid) (PMLA) nanoplatform for TNBC treatment. The nanobioconjugate carriesanti-tumor nucleosome-specific monoclonal antibody (mAb) 2C5...

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Literature Corpus work: cae1b4dc-9925-5c2c-987d-267c642e188a
DOI: 10.31234/osf.io/p6tuk

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