Article
Clustering-based time series analysis on insulin response in the blood-brain barrier
2021-03-08
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Background</h4> Critical functions of the blood-brain barrier (BBB), including cerebral blood flow and vascular response, are regulated by insulin signaling pathways. Therefore, endothelial insulin resistance could lead to vascular dysfunction, which is associated with neurodegenerative diseases such as Alzheimer’s disease (AD). <h4>Objective</h4> The objective of the current study is to m...
Topics
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- Adipose Tissue and Metabolism
- Alzheimer's disease research and treatments
- Barrier Structure and Function Studies
- Bioinformatics and Genomic Networks
- Cerebrovascular and genetic disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Sirtuins and Resveratrol in Medicine
Identifiers and source
- Literature Corpus work
- cade98cb-5f21-5d31-9302-6501ac0a6635
- DOI
- 10.1101/2021.03.07.434315
