Article

Hyperglycemic conditions induce rapid cell dysfunction-promoting transcriptional alterations in human aortic endothelial cells

2022-06-17

Abstract excerpt

Hyperglycemia is a major risk factor in the development of diabetic complications and promotes vascular complications through dysregulation of endothelial cell function. Various mechanisms have been proposed for endothelial cell dysregulation but the early transcriptomic alterations of endothelial cells under hyperglycemic conditions are not well documented. Here we use deep time-series RNA-seq profiling of human...

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Literature Corpus work: aa83e433-f38b-5390-9d25-72a8e5b7fe60
DOI: 10.21203/rs.3.rs-1734028/v1

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