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A Novel multifunctional 5,6-dimethoxy-indanone-chalcone-carbamate hybrids alleviates cognitive decline in Alzheimer’s disease by dual inhibition of acetylcholinesterase and inflammation

2022-03-23

Abstract excerpt

<h4>Backgrounds: </h4>: Alzheimer's disease (AD) is a multifactorial neurodegenerative disease. The treatment of AD through multiple pathological targets may generate therapeutic efficacy better. The multifunctional molecules that simultaneously hit several pathological targets have been of great interest in intervention of AD. <h4>Methods: </h4>: Here we combined the chalcone scaffold with carbamate moiety and 5,...

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Literature Corpus work
ca82c61f-fabd-54db-8eed-07f0a8862bb3
DOI
10.21203/rs.3.rs-1467420/v1
Open publication

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A Novel multifunctional 5,6-dimethoxy-indanone-chalcone-carbamate hybrids alleviates cognitive decline in Alzheimer’s disease by dual inhibition of acetylcholinesterase and inflammationDOI 10.21203/rs.3.rs-1467420/v1
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