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Rational Design and In Silico Evaluation of Benzimidazole-Fused Pyran Derivatives as Acetylcholinesterase Inhibitors for Alzheimer’s Disease

2026-04-17

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<title>Abstract</title> <p> Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by cholinergic dysfunction, for which acetylcholinesterase (AChE) inhibition remains a clinically validated symptomatic treatment strategy. In the present study, a series of benzimidazole-dihydropyran hybrid derivatives ( <bold>4a-n</bold> ) were rationally designed and evaluated using an integrated computat...

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Literature Corpus work
b781f941-a4de-50a5-9efc-5b7cf07fd3e7
DOI
10.21203/rs.3.rs-8993822/v1
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Rational Design and In Silico Evaluation of Benzimidazole-Fused Pyran Derivatives as Acetylcholinesterase Inhibitors for Alzheimer’s DiseaseDOI 10.21203/rs.3.rs-8993822/v1
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