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The Alzheimer’s disease drug development landscape

11 Nov 2021

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a devastating neurodegenerative disease leading to dementia. The field has made significant progress over the last 15 years. AD diagnosis has shifted from syndromal, based on signs and symptoms, to a biomarker construct based on the pathological hallmarks of the disease: amyloid β deposition, pathologic tau, and neurodegeneration. Numerous genetic risk factors for sporadic...

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PMID: 34763720
DOI: 10.1186/s13195-021-00927-z

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