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Article

Analysis of skeletal diversity of multi-target directed ligands (MTDLs) targeting Alzheimer's disease

17 Jan 2025

Abstract excerpt

Alzheimer's disease (AD) remains a significant healthcare challenge, necessitating innovative therapeutic approaches to address its complex and multifactorial nature. Traditional drug discovery strategies targeting single molecular targets are not sufficient for the effective treatment of AD. In recent years, MTDLs have emerged as promising candidates for AD therapy, aiming to simultaneously modulate multiple...

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PMID: 39848035
DOI: 10.1016/j.ejmech.2025.117277

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