Article

Regulator of calcineurin-2 is a centriolar protein with a role in cilia length control

2017-09-19

Abstract excerpt

Almost every cell in the human body extends a primary cilium. Defective cilia function leads to a set of disorders known as ciliopathies characterised by debilitating developmental defects affecting many tissues. Here we report a new role for regulator of calcineurin 2, RCAN2, in primary cilia function. It localises to centrioles and the basal body and is required to maintain normal cilia length. RCAN2 was identif...

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Literature Corpus work: ca049137-4f97-5491-a011-bd4a106448a5
DOI: 10.1101/188946

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