Article

Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage

2022-05-10

Abstract excerpt

<h4>Background: </h4> Microglial necroptosis exacerbates neurodegenerative diseases, central nervous system injury and demonstrates a pro-inflammatory process, but its contribution to subarachnoid hemorrhage (SAH) is poorly characterized. BCL-2 homologous antagonist-killer protein (Bak1), a critical regulatory molecule of endogenous apoptosis, can be involved in the pathological process of necroptosis by regulatin...

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Literature Corpus work: c9c3ab0f-7f1a-57c0-b3ec-b5fb45cc4903
DOI: 10.21203/rs.3.rs-1515494/v2

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