Article

SARS-CoV-2 infection of human brain microvascular endothelial cells leads to inflammatory activation through NF-κB non-canonical pathway and mitochondrial remodeling

2022-06-16

Abstract excerpt

<h4>ABSTRACT</h4> Neurological effects of COVID-19 and long-COVID-19 as well as neuroinvasion by SARS-CoV-2 still pose several questions and are of both clinical and scientific relevance. We described the cellular and molecular effects of the human brain microvascular endothelial cells (HBMECs) in vitro infection by SARS-CoV-2 to understand the underlying mechanisms of viral transmigration through the Blood-Brai...

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Literature Corpus work: 14151454-b551-5230-909e-259bd25b2342
DOI: 10.1101/2022.06.16.496324

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