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BTK promotes neuroinflammation by interacting with hub genes and modulating microglia following intracerebral hemorrhage

2026-03-06

Abstract excerpt

<h4>ABSTRACT</h4> Bruton’s tyrosine kinase (BTK) has been reported to be important in the inflammatory response in many diseases. However, its role and explicit mechanisms in intracerebral hemorrhage (ICH) remain unclear. Here, we used a mouse ICH model and transcriptomic datasets to explore the effect of BTK on neuroinflammation after ICH. Inhibiting BTK with ibrutinib alleviated ICH-induced neurological deficit...

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Literature Corpus work
a2987cfa-7811-58cb-8f26-8aaac75e5606
DOI
10.64898/2026.03.04.709243
Open publication

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BTK promotes neuroinflammation by interacting with hub genes and modulating microglia following intracerebral hemorrhageDOI 10.64898/2026.03.04.709243
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