Article

Codeletion ofCDKN2 andMTAP genes in a subset of non-Hodgkin's lymphoma may be associated with histologic transformation from low-grade to diffuse large-cell lymphoma

1998-05-01

Abstract excerpt

Identifying the various genetic alterations that contribute to lymphomagenesis is key to our improved understanding of the biological behavior of the disease. Recently, we and others have defined a tumor suppressor region on the short arm of chromosome 9 harboring a cluster of genes, including MTAP, CDKN2A(p16INK4a), and CDKN2B(p15INK4B), which is frequently deleted in a variety of tumor types. To determine whethe...

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Literature Corpus work: c90cac61-ea19-538c-9baf-132ad4ba9e17
DOI: 10.1002/(sici)1098-2264(199805)22:1<72::aid-gcc10>3.0.co;2-k

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