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Chromosomal Translocations Involved in Non-Hodgkin Lymphomas

1 Sept 2003

Abstract excerpt

CONTEXT: The discovery that recurrent chromosomal translocations are involved in the pathogenesis of non-Hodgkin lymphomas has greatly improved our understanding of these diseases and revolutionized their diagnosis. OBJECTIVE: To review the mechanisms by which chromosomal translocations occur and contribute to the pathogenesis of various types of non-Hodgkin lymphomas and to review the utility of molecular...

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PMID: 12946230
DOI: 10.5858/2003-127-1148-ctiinl

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