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Reference-free Analysis of scRNA-seq Data Reveals Elevated rRNA and mtRNA Transcription during Neurogenesis in Axolotl

2024-11-18

Abstract excerpt

Analysis of single-cell RNA-seq data is typically performed on a gene expression matrix estimated by aligning reads to a reference transcriptome. However, this approach is difficult to apply to organisms with no or incomplete reference transcriptomes. In addition, events deviating from the reference remain undetected. Here we present a reference-free method to analyze single-cell RNA-seq data based on k -mers. We...

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Literature Corpus work
c900b986-6b70-5fc1-a848-0004de71cceb
DOI
10.1101/2024.11.18.624113
Open publication

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Reference-free Analysis of scRNA-seq Data Reveals Elevated rRNA and mtRNA Transcription during Neurogenesis in AxolotlDOI 10.1101/2024.11.18.624113
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