Article
Reference-free Analysis of scRNA-seq Data Reveals Elevated rRNA and mtRNA Transcription during Neurogenesis in Axolotl
2024-11-18
Abstract excerpt
Analysis of single-cell RNA-seq data is typically performed on a gene expression matrix estimated by aligning reads to a reference transcriptome. However, this approach is difficult to apply to organisms with no or incomplete reference transcriptomes. In addition, events deviating from the reference remain undetected. Here we present a reference-free method to analyze single-cell RNA-seq data based on k -mers. We...
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Identifiers and source
- Literature Corpus work
- c900b986-6b70-5fc1-a848-0004de71cceb
- DOI
- 10.1101/2024.11.18.624113
