Article

Intron retention, a novel method for evaluating the response to ketamine in patients with treatment-resistant depression

2025-01-30

Abstract excerpt

<title>Abstract</title> <p>In response to a state of stress, the body attempts to maintain protein homeostasis through intron retention (IR). In other words, by examining which genes undergo IR under stress (i.e., IR genes), it is possible to analyze what type of stress the body is experiencing (Okada et al. 2024 Front.Psychiatry). Using this principle, we re-analyzed the RNA-seq data of non-responders and respon...

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Literature Corpus work: c8f0bbf2-5c69-5a93-8c51-68cebacba147
DOI: 10.21203/rs.3.rs-5823020/v1

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