Article

Mtor Gene Variants are Associated with Severe Covid-19 Outcomes: A Multicenter Study

2023-09-08

Abstract excerpt

Background: The worst outcomes linked to SARS-CoV-2 infection have been attributed to the cytokine storm, which contributes significantly to the immunopathogenesis of the disease. The mTOR pathway is essential for orchestrating innate immune cell defense including cytokine production and is dysregulated in severe COVID-19 individuals. The individual genetic background might play a role in the exacerbated immune re...

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Literature Corpus work: c8c3deb0-abc6-59c4-8afa-33e4c078432e
DOI: 10.2139/ssrn.4562006

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