Article

Mapping RNA dependent RNA polymerase activity and immune gene expression using PRO-seq

2020-06-16

Abstract excerpt

<h4>Summary</h4> Positive strand, single strand RNA viruses ((+)ssRNA viruses) are viruses with an RNA genome that have broad impacts on a wide range of hosts, including SARS-CoV-2 human respiratory infections. Their replication and gene expression are driven by RNA dependent RNA polymerases (RdRp). Detecting active RNA synthesis by RdRp is critical for assessing the infectivity and pathogenicity of (+)ssRNA viru...

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Literature Corpus work: c87336b9-01dd-509e-9dbf-d8d5eb615dc4
DOI: 10.1101/2020.06.15.151738

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