Article
Detection of viral sequences at single-cell resolution identifies novel viruses associated with host gene expression changes
22 Apr 2025
Abstract excerpt
The increasing use of high-throughput sequencing methods in research, agriculture and healthcare provides an opportunity for the cost-effective surveillance of viral diversity and investigation of virus-disease correlation. However, existing methods for identifying viruses in sequencing data rely on and are limited to reference genomes or cannot retain single-cell resolution through cell barcode tracking. We...
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