Article

Novel RT-ddPCR Assays for determining the transcriptional profile of SARS-CoV-2

2021-01-12

Abstract excerpt

The exact mechanism of coronavirus replication and transcription is not fully understood; however, a hallmark of coronavirus transcription is the generation of negative-sense RNA intermediates that serve as the templates for the synthesis of positive-sense genomic RNA (gRNA) and an array of subgenomic mRNAs (sgRNAs) encompassing sequences arising from discontinuous transcription. Existing PCR-based diagnostic assa...

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Literature Corpus work: 66524452-381d-5fdb-ab01-8fb626e3ad30
DOI: 10.1101/2021.01.12.425991

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