Article

A humanized breast cancer microorganoid platform for the ranked evaluation of tumor microenvironment-targeted drugs by light sheet fluorescence microscopy

2023-12-02

Abstract excerpt

<title>Abstract</title> Targeting the supportive tumor microenvironment (TME) is an approach of high interest in cancer drug development. However, assessing TME-targeted drug candidates presents a unique set of challenges: Adequate assays need to recreate the TME at least in part and provide intricate information about drug-induced changes in the TME’s interactions. We have developed a comprehensive screening...

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Literature Corpus work: c83ee4da-955c-5064-bb00-27e7184551b1
DOI: 10.21203/rs.3.rs-3627627/v1

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