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Translation of a Tumor Microenvironment Mimicking 3D Tumor Growth Co-culture Assay Platform to High-Content Screening

25 Aug 2012

Abstract excerpt

For drug discovery, cell-based assays are becoming increasingly complex to mimic more realistically the nature of biological processes and their diversifications in diseases. Multicellular co-cultures embedded in a three-dimensional (3D) matrix have been explored in oncology to more closely approximate the physiology of the human tumor microenvironment. High-content analysis is the ideal technology to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22923784
DOI: 10.1177/1087057112456874

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