Article

Transcriptomic differences between fibrotic and non-fibrotic testicular tissue reveal possible key players in Klinefelter syndrome-related testicular fibrosis

2022-06-28

Abstract excerpt

<h4>Background: </h4> Klinefelter syndrome (KS; 47,XXY) affects 1-2 in 1000 males. Most KS men suffer from an early germ cell loss and testicular fibrosis from puberty onwards. Mechanisms responsible for these processes remain unknown. Previous genomics studies on KS tissue focused on germ cell loss, while a transcriptomic analysis focused on testicular fibrosis has not yet been performed. This study aimed to iden...

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Literature Corpus work: c83e633a-6788-5ef5-a309-6bc571da144c
DOI: 10.21203/rs.3.rs-1745658/v2

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