Article

Genes and pathways underpinning Klinefelter syndrome at the single-cell level

2023-08-29

Abstract excerpt

Klinefelter syndrome (KS) is the most frequent genetic anomaly in infertile males. Despite this, the molecular mechanisms involved in KS are poorly defined. Based on bulk transcriptome and single-cell RNA sequencing datasets with peripheral blood monocyte (PBMC) sample(s) from healthy and KS men, this study was designed to address critical genes and pathways correlated with the occurrence of KS. Through a comparis...

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Literature Corpus work: 98ccdabb-9f16-50a6-bf16-df8834d5a17b
DOI: 10.21203/rs.3.rs-3285636/v1

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