Article
Decoding the pathogenesis of spermatogenic failure in cryptorchidism through single-cell transcriptomic profiling
1 Sept 2024
Abstract excerpt
Cryptorchidism, commonly known as undescended testis, affects 1%–9% of male newborns, posing infertility and testis tumor risks. Despite its prevalence, the detailed pathophysiology underlying male infertility within cryptorchidism remains unclear. Here, we profile and analyze 46,644 single-cell transcriptomes from individual testicular cells obtained from adult males diagnosed with cryptorchidism and healthy...
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