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Article

Expression-based prediction of human essential genes and candidate lncRNAs in cancer cells

6 Aug 2020

Abstract excerpt

MOTIVATION: Essential genes are required for the reproductive success at either cellular or organismal level. The identification of essential genes is important for understanding the core biological processes and identifying effective therapeutic drug targets. However, experimental identification of essential genes is costly, time consuming and labor intensive. Although several machine learning models have been...

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PMID: 32790840
DOI: 10.1093/bioinformatics/btaa717

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