Article

Accurate prediction of human essential genes using only nucleotide composition and association information

2016-10-28

Abstract excerpt

Three groups recently identified essential genes in human cancer cell lines using wet experiments, and these genes are of high values. Herein, we improved the widely used Z curve method by creating a λ-interval Z curve, which considered interval association information. With this method and recursive feature elimination technology, a computational model was developed to predict human gene essentiality. The 5-fold...

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Literature Corpus work: 93a6bdfa-3903-5b7a-88d8-fe356d3b9723
DOI: 10.1101/084129

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