Article

Generation of “OP7 chimera” defective interfering particle preparations free of infectious influenza A virus that shows antiviral efficacy in mice

2023-08-17

Abstract excerpt

Influenza A virus (IAV) defective interfering particles (DIPs) are considered as new promising antiviral agents. Conventional DIPs (cDIPs) contain a deletion in the genome and can only replicate upon co-infection with infectious standard virus (STV), during which they suppress STV replication. We previously discovered a new type of IAV DIP “OP7” that entails genomic point mutations and displays higher antiviral ef...

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Literature Corpus work: c82400a1-e308-5690-8871-0ba65e12c1b6
DOI: 10.1101/2023.08.16.553516

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