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Article

Leveraging ancient DNA to uncover signals of natural selection in Europe lost due to admixture or drift.

Nature communications - 12 Nov 2024

Pandey Devansh, Harris Mariana, Garud Nandita R, Narasimhan Vagheesh M

Abstract excerpt

Large ancient DNA (aDNA) studies offer the chance to examine genomic changes over time, providing direct insights into human evolution. While recent studies have used time-stratified aDNA for selection scans, most focus on single-locus methods. We conducted a multi-locus genotype scan on 708 samples spanning 7000 years of European history. We show that the G12 statistic, originally designed for unphased diploid...

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Identifiers

PMID: 39532856
DOI: 10.1038/s41467-024-53852-8
PMCID: PMC11557891

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