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The clinical utility of two high-throughput 16S rRNA gene sequencing workflows for taxonomic assignment of unidentifiable bacterial pathogens in MALDI-TOF MS

2021-08-17

Abstract excerpt

<h4>ABSTRACT</h4> Bacterial pathogens that cannot be identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) are occasionally encountered in clinical laboratories. The 16S rRNA gene is often used for sequence-based analysis to identify these bacterial species. Nevertheless, traditional Sanger sequencing is laborious, time-consuming and low-throughput. Here, we...

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Literature Corpus work
c7d39ea2-a1dd-56cc-b352-a7bce5bf3a68
DOI
10.1101/2021.08.16.456588
Open publication

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