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The application of targeted nanopore sequencing for the identification of pathogens and resistance genes in lower respiratory tract infections

22 Dec 2022

Abstract excerpt

Objectives Lower respiratory tract infections (LRTIs) are one of the causes of mortality among infectious diseases. Microbial cultures commonly used in clinical practice are time-consuming, have poor sensitivity to unculturable and polymicrobial patterns, and are inadequate to guide timely and accurate antibiotic therapy. We investigated the feasibility of targeted nanopore sequencing (TNPseq) for the...

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PMID: 36620015
DOI: 10.3389/fmicb.2022.1065159

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