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Optimizing and Evaluating Nanopore-Based Targeted and Metagenomic Sequencing Workflows for Rapid Diagnosis of Acute Invasive Infections from Normally Sterile Body Fluids

2025-06-02

Abstract excerpt

Rapid and accurate pathogen identification is critical for managing acute invasive infections. Conventional culture methods are time-consuming, delaying effective treatment. Nanopore sequencing offers real-time, long-read capabilities suitable for clinical diagnostics, yet standardized workflows remain lacking. This study developed and evaluated two optimized nanopore sequencing workflows: Nanopore Targeted Sequen...

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Literature Corpus work
ff8e81ee-940f-548b-83da-4cafb3e8060b
DOI
10.1101/2025.06.02.25328768
Open publication

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Optimizing and Evaluating Nanopore-Based Targeted and Metagenomic Sequencing Workflows for Rapid Diagnosis of Acute Invasive Infections from Normally Sterile Body FluidsDOI 10.1101/2025.06.02.25328768
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