Back to search

Article

Identification and Evaluation of dibasic piperidines as novel cell wall inhibitors against <i>Mycobacterium tuberculosis</i>

2026-01-30

Abstract excerpt

Globally, Mycobacterium tuberculosis remains a significant disease burden. Although effective treatment regimens exist, drug resistance continues to emerge. This clinical resistance, combined with side effects and protracted treatment times from the current front-line therapies, means there is a need to identify novel agents to combat this disease. Here we report on a new chemical series, identified by whole-cell...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c7ad3dba-c9c9-5d9f-aa50-d4742fac2092
DOI
10.64898/2026.01.30.702510
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Identification and Evaluation of dibasic piperidines as novel cell wall inhibitors against <i>Mycobacterium tuberculosis</i>DOI 10.64898/2026.01.30.702510
Identification of the anti-mycobacterial functional properties of piperidinol derivatives.Semantic proximity
Strategies in anti-Mycobacterium tuberculosis drug discovery based on phenotypic screeningSemantic proximity
Discovery of Novel Acetohydroxyacid Synthase Inhibitors as Active Agents against<i>Mycobacterium tuberculosis</i>by Virtual Screening and BioassaySemantic proximity
Synthesis and Biological Aspects of Mycolic Acids: An Important Target Against<i>Mycobacterium tuberculosis</i>Semantic proximity
Development of Mycobacterium tuberculosis whole cell screening hits as potential antituberculosis agents.Semantic proximity
<i>α</i> -Aminooxyacetic acid derivatives acting as pro-drugs against <i>Mycobacterium tuberculosis</i>Semantic proximity
Biological Profiling Enables Rapid Mechanistic Classification of Phenotypic Screening Hits and Identification of KatG Activation-Dependent Pyridine Carboxamide Prodrugs With Activity Against Mycobacterium tuberculosis.Semantic proximity
Development of amidase-dependent pyrazinoic acid prodrugs with activity against pyrazinamide resistant <i>Mycobacterium tuberculosis</i>Semantic proximity
Azetidines kill <i>Mycobacterium tuberculosis</i> without detectable resistance by blocking mycolate assemblySemantic proximity
Utilisation of the Prestwick Chemical Library <sup>®</sup> to identify drugs that inhibit the growth of MycobacteriaSemantic proximity
Diaza-anthracene Antibiotics from a Freshwater-Derived Actinomycete with Selective Antibacterial Activity toward <i>Mycobacterium tuberculosis</i>Semantic proximity
Construction of <i>lux</i> -based promoter-reporter platforms in <i>Mycobacterium bovis</i> BCG for screening of drug repurposing small-molecule compounds as new anti-tuberculosis drugsSemantic proximity
Select a neighboring publication to make it the new centre.