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Article

Development of Mycobacterium tuberculosis whole cell screening hits as potential antituberculosis agents.

Journal of medicinal chemistry - 24 Oct 2013

Cooper Christopher B

Abstract excerpt

The global pandemic of drug sensitive tuberculosis (TB) as well as the increasing threat from various multidrug resistant forms of TB drives the quest for newer, safer, more effective TB treatment options. The general lack of success in progressing novel chemical matter from high throughput screens of Mycobacterium tuberculosis (M.tb) biochemical targets has prompted resurgence in interest and efforts in...

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PMID: 23927683
DOI: 10.1021/jm400381v

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