Article

Recent advances in pharmacogenetic approaches to anticancer drug development

2004-07-01

Abstract excerpt

Abstract A great deal of effort has been spent in defining the pharmacokinetics and pharmacodynamics of investigational and registered anticancer agents. There is often a marked variability in drug handling between individual patients, which contributes to variability in the pharmacodynamic effects of a given dose of a drug. A combination of physiological variables, genetic characteristics (pharmacogenetics), and...

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Literature Corpus work: c7a7fbae-f806-5b95-80a5-d39cbdce9a81
DOI: 10.1002/ddr.10361

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