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Article

Pharmacogenomics of drug-metabolizing enzymes and drug transporters in chemotherapy.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008

Bosch Tessa M

Abstract excerpt

There is wide variability in the response of individuals to standard doses of drug therapy. This is an important problem in clinical practice, where it can lead to therapeutic failures or adverse drug events. Polymorphisms in genes coding for metabolizing enzymes and drug transporters can affect drug efficacy and toxicity. Pharmacogenomics aims to identify individuals predisposed to high risk of toxicity and low...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18370231
DOI: 10.1007/978-1-59745-205-2_5

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TPMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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