Article

Evaluation of AlphaFold3 for the fatty acids docking to human fatty acid-binding proteins

2024-07-25

Abstract excerpt

Human fatty acid-binding proteins (FABPs) are involved in many aspects of lipid metabolism, such as the uptake, transport, and storage of lipophilic molecules, as well as cellular functions. Understanding how FABPs recognize fatty acids (FAs) is crucial for identifying FABP function and applications, such as in inhibitor design or biomarker development. The recently developed AlphaFold3 (AF3) demonstrates signific...

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Literature Corpus work: c770dd23-721f-5674-a0b6-6f924e01d0bc
DOI: 10.1101/2024.07.25.605175

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