Article

PI 3-kinase : a key effector in C-FMS signalling

1999-01-01

Abstract excerpt

Aberrant regulation of macrophage recruitment and activation by M-CSF is integral to inflammatory disease and cancer. M-CSF stimulated responses are mediated by the <i>c-fms</i> gene product found on monocytes and macrophages. A key component of signalling pathways immediately downstream of <i>c-fms</i> is Phosphatidylinositol 3-kinase. The research data presented in this thesis examined the role of PI 3-kinase in...

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Literature Corpus work: c76f2ef9-804f-518f-934d-66b8fb93e3c9
DOI: 10.21954/ou.ro.00010206

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