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Investigating the role of the relaxin-3/RXFP3 system in neuropsychiatric disorders and metabolic phenotypes: a candidate gene approach

2023-08-16

Abstract excerpt

The relaxin-3/RXFP3 system has been implicated in the modulation of depressive- and anxiety-like behaviour in the animal literature; however, there is a lack of human studies investigating this signalling system. We seek to bridge this gap by leveraging the large UK Biobank study to retrospectively assess genetic risk variants linked with this neuropeptidergic system. Specifically, we conducted a candidate gene st...

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Literature Corpus work
c75fef11-e5f3-578d-8da6-20468e59d88c
DOI
10.1101/2023.08.13.23294038
Open publication

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Investigating the role of the relaxin-3/RXFP3 system in neuropsychiatric disorders and metabolic phenotypes: a candidate gene approachDOI 10.1101/2023.08.13.23294038
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