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Article

Nonsynonymous Variation in NKPD1 Increases Depressive Symptoms in European Populations.

Biological psychiatry - 15 Apr 2017

Amin Najaf, Belonogova Nadezhda M, Jovanova Olivera, Brouwer Rutger W W, van Rooij Jeroen G J, van den Hout Mirjam C G N, Svishcheva Gulnara R, Kraaij Robert, Zorkoltseva Irina V, Kirichenko Anatoly V, Hofman Albert, Uitterlinden André G, van IJcken Wilfred F J, Tiemeier Henning, Axenovich Tatiana I, van Duijn Cornelia M

Abstract excerpt

BACKGROUND: Despite high heritability, little success was achieved in mapping genetic determinants of depression-related traits by means of genome-wide association studies. METHODS: To identify genes associated with depressive symptomology, we performed a gene-based association analysis of nonsynonymous variation captured using exome-sequencing and exome-chip genotyping in a genetically isolated population from...

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PMID: 27745872
DOI: 10.1016/j.biopsych.2016.08.008

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NKPD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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