Article

ATM modulates nuclear mechanics by regulating lamin A levels

2022-03-01

Abstract excerpt

Ataxia-telangiectasia mutated (ATM) is one of the three main apical kinases at the crux of DNA damage response and repair in mammalian cells. ATM activates a cascade of downstream effector proteins to regulate DNA repair and cell cycle checkpoints in response to DNA double-strand breaks. While ATM is predominantly known for its role in DNA damage response and repair, new roles of ATM have recently begun to emerge,...

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Identifiers and source

Literature Corpus work: c71bc9f2-494e-57e1-9f9e-ff401a2a2d18
DOI: 10.1101/2022.02.28.482418

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