Article
The Fall of the Armor: Lamin Dysregulation and a Wide Network of Laminopathies.
Sub-cellular biochemistry - 1 Jan 2025
Ray Hrishee, Kundu Tapas K
Abstract excerpt
The nuclear membrane of cells harbors a lamina as a critical structural component beneath itself which serves as a dynamic scaffold that maintains nuclear integrity and cellular homeostasis. The primary component of the nuclear lamina is lamins, a set of type V intermediate filament proteins, which form a meshwork to provide mechanical stability while modulating essential biological processes like DNA...
Topics
- Humans
- Laminopathies
- Lamins
- Animals
- Nuclear Lamina
- Neoplasms
- Mutation
- Muscular Dystrophies