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Mesenchymal stem cell derived proteome can target multiple signalling pathways to ameliorate rheumatoid arthritis: network pharmacology and molecular docking based approach

2024-04-10

Abstract excerpt

<title>Abstract</title> <p>Rheumatoid arthritis (RA) is an autoimmune chronic inflammatory disease with a global prevalence of approximately 1%. Mesenchymal stem cells (MSCs) have been thoroughly investigated for the treatment of RA; however, their clinical use is limited due to issues related to cell engraftment. It is now well established that MSCs exert their regenerative effect through the paracrine mechanism...

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Literature Corpus work
1c983934-c996-5bde-bb8e-283062ced35c
DOI
10.21203/rs.3.rs-4182815/v1
Open publication

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