Article

Recombinant VEGF-C (Cys156Ser) protein restores mesenteric lymphatic drainage and improves gut immune surveillance in experimental liver cirrhosis

2020-12-27

Abstract excerpt

<h4>Background and Aim</h4> Lymphatic vessels (LVs) are crucial for maintaining abdominal fluid homeostasis and immunity. In liver cirrhosis, mesenteric LVs (mLVs) are dilated and dysfunctional. Given an established protective role of VEGF-C in LVs, we hypothesized that VEGF-C treatment could improve functions of mLVs in cirrhosis. <h4>Method</h4> In this study, we developed a nanoformulation comprising LV-specifi...

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Literature Corpus work: c6e3b873-e2e5-5197-bb52-dcbd7d0c9a95
DOI: 10.1101/2020.12.24.20248815

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Recombinant VEGF-C (Cys156Ser) protein restores mesenteric lymphatic drainage and improves gut immune surveillance in experimental liver cirrhosisDOI 10.1101/2020.12.24.20248815Read

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