Article

A phase I clinical trial of intrahepatic artery delivery of TG6002 in combination with oral 5-fluorocytosine in patients with liver-dominant metastatic colorectal cancer

2024-07-31

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Effective treatment for patients with metastatic cancer is limited, particularly for colorectal cancer patients with metastatic liver lesions (mCRC), where accessibility to numerous tumours is essential for favourable clinical outcomes. Oncolytic viruses (OVs) selectively replicate in cancer cells; however, direct targeting of inaccessible lesions is limited when using convent...

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Literature Corpus work: a9ffcd90-c962-54a8-a655-de1d53b32d63
DOI: 10.1101/2024.07.30.24311046

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