Article
A primate virus generates transformed human cells by fusion.
The Journal of cell biology - 7 Nov 2005
Duelli Dominik M, Hearn Stephen, Myers Michael P, Lazebnik Yuri
Abstract excerpt
Amodel that explains both the origin and sporadic nature of cancer argues that cancer cells are a chance result of events that cause genomic and epigenetic variability. The prevailing view is that these events are mutations that affect chromosome segregation or stability. However, genomic and epigenetic variability is also triggered by cell fusion, which is often caused by viruses. Yet, cells fused by viruses are...
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