Article

Choline and Alpha-GPC's as Neuroprotective Agents in Alzheimer's Disease: Mechanisms Involving APOE-ε4-Mediated Neurodegeneration

2026-01-08

Abstract excerpt

Alzheimer's disease (AD) remains one of the most prevalent neurodegenerative conditions worldwide, affecting over 3 million Americans annually with no current cure. The APOE-ε4 allele is a significant genetic risk factor for AD, present in 15-25% of the population. This literature review examines emerging evidence suggesting that choline, a phospholipid structural component essential for cellular metabolism, may s...

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Literature Corpus work: c68dac35-1160-55bf-97b2-4bc7088f9bce
DOI: 10.22541/au.176790837.74739158/v1

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