Article

Different spatial profiles of aberrant N-glycans in pediatric and adult MOGHE brain tissue

2026-08-18

Abstract excerpt

Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is a recently recognized epilepsy-associated lesion frequently linked to brain-restricted somatic variants in SLC35A2 , a gene encoding the Golgi UDP-galactose transporter. Although previous studies demonstrated altered glycosylation in SLC35A2 -mutated MOGHE tissue, the spatial relationship between glycosylation defe...

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Literature Corpus work: c66d553d-af68-534e-8df9-18ae60579c12
DOI: 10.64898/2026.08.12.744424

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