Article

High hyperdiploid karyotype with ≥49 chromosomes represents a heterogeneous subgroup of acute myeloid leukemia with differential TP53 mutation status and prognosis: a single-center study from China

2024-03-05

Abstract excerpt

<title>Abstract</title> <p>High hyperdiploid karyotype with ≥49 chromosomes (which will be referred to as HHK) is rare in acute myeloid leukemia (AML). The European leukemia network (ELN) excluded those harboring only numerical changes (with ≥3 chromosome gains) from CK and listed them in the intermediate risk group, while the UK National Cancer Research Institute Adult Leukaemia Working Group classification defi...

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Literature Corpus work: c6478e8c-84d6-5b61-800d-6d4ad2ddb7f3
DOI: 10.21203/rs.3.rs-3974735/v1

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