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Article

Single nucleotide polymorphism array-based signature of low hypodiploidy in acute lymphoblastic leukemia.

Genes, chromosomes & cancer - 1 Sept 2021

Creasey Thomas, Enshaei Amir, Nebral Karin, Schwab Claire, Watts Kathryn, Cuthbert Gavin, Vora Ajay, Moppett John, Harrison Christine J, Fielding Adele K, Haas Oskar A, Moorman Anthony V

Abstract excerpt

Low hypodiploidy (30-39 chromosomes) is one of the most prevalent genetic subtypes among adults with ALL and is associated with a very poor outcome. Low hypodiploid clones can often undergo a chromosomal doubling generating a near-triploid clone (60-78 chromosomes). When cytogenetic techniques detect a near triploid clone, a diagnostic challenge may ensue in differentiating presumed duplicated low hypodiploidy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33938069
DOI: 10.1002/gcc.22956
PMCID: PMC8600946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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